Spatial Transcriptomics

Spatial Transcriptomics is a molecular profiling method to determine the cellular localization of mRNA molecules on a tissue section. This has been chosen as the method of the year by Nature magazine in 2020.
 
The Genomics Core Facility has established the NanoString’s GeoMx Digital Spatial Profiler technology as a service and is currently working on the establishment of the 10x Genomics Visium technology. 
 
The NanoString’s GeoMx Digital Spatial Profiler (DSP) combines spatial and molecular profiling technologies by generating digital whole transcriptomes and profiling data for 100s of validated Protein analytes. This unique combination of high-plex and high-throughput spatial profiling enables researchers to rapidly and quantitatively assess the biological implications of the heterogeneity within tissue samples. For more information about DSP applications please visit this NanoString website.
 

Technology overview

 

Example from our services

Morphology marker PanCK (green), CD45 (grey), SYTO13 (blue) & Vimentin (red) Morphology on a gastrointestinal stromal tumours.

 
 
 
 

News

Aug 4, 2022
New I.DOT installed
Our new Dispendix I.DOT DW microfluidic non-contact liquid handling system is installed.
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May 31, 2022
Summer Closure 2022

The Genomics Core Facility will not be accepting new sample submissions over the summer break. The deadline for submission is 1 PM on Friday 8th of July. We will reopen again on Monday 1st of August. The sequencing of existing projects will continue, although turnaround times may be longer than usual.

We wish all our users a good summer

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Contact Information:

Genomics@rr-research.no

Unit Leader Core Facility
Susanne Lorenz, PhD

Susanne.Lorenz@rr-research.no

Head of Core Facility
Leonardo A. Meza-Zepeda, Dr. philos.

Leonardo.A.Meza-Zepeda@rr-research.no

Follow us via Twitter

@OSLOmicsCore

Visiting address:

Genomics Core Facility (Room 3-F8-04)
Department of Core facilities
Institute for Cancer Research
New OCCI-building  
Norwegian Radium Hospital 
Ullernchaussen 66, Lamell 3, 2B 
NO-0379 Oslo, NORWAY

+47 - 9183 2772 Laboratory
+47 - 9183 3425 Office

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