Single-Cell Analysis Platform

The Genomics Core Facility offers a wide variety of single-cell sequencing workflows to study heterogeneity within the epigenome, genome, transcriptome, and proteome at a single-cell resolution. Services are provided using the 10x Genomics Chromium and the BD Rhapsody platform.

These technologies allow the processing of thousands of single cells for downstream molecular analysis. DNA and RNA from every single cell can be barcoded and further investigated using high-throughput sequencing.
 
We collaborate with our local Flow Cytometry, Advanced Light Microscopy and Bioinformatics Core Facilities at the Institute for Cancer Research to deliver a complete workflow for single-cell analysis. 
 
Ana_SC
Applications established for service:
  • Single-cell immune profilingsequencing of the full V(D)J region for quantitative  -cell and B-cell characterization (Chromium & Rhapsody)
  • Single Cell ATAC: (Assay for Transposase Accessible Chromatin): allows chromatin accessibility profiling of tens of thousands of single cells in parallel
  • Single-cell multiome: Simultaneously profile gene expression and open chromatin from the same cell with Chromium Single Cell Multiome ATAC + Gene Expression.

We are working to establish additional applications: Single nuclei RNA-Seq.

Contact us for additional information or information meeting

 
 
 
 


News

Oct 25, 2022
The Oslo University Hospital and University of Oslo Genomics Core Facility in collaboration with 10x Genomics will launch the new multiomics platform established in Norway.
Oct 6, 2022
The Genomics Core Facility has installed a new high-throughput QuantStudio5 384-well real-time PCR instrument.


Contact Information:

Genomics@rr-research.no

Unit Leader Core Facility
Susanne Lorenz, PhD

Susanne.Lorenz@rr-research.no

Head of Core Facility
Leonardo A. Meza-Zepeda, Dr. philos.

Leonardo.A.Meza-Zepeda@rr-research.no

Follow us via Twitter

@OSLOmicsCore

Visiting address:

Genomics Core Facility (Room 3-F8-04)
Department of Core facilities
Institute for Cancer Research
New OCCI-building 
 
Norwegian Radium Hospital 
Ullernchaussen 66, Lamell 3, 2B 
NO-0379 Oslo, NORWAY

+47 - 9183 2772 Laboratory
+47 - 9183 3425 Office

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