Mar 2, 2023

RRBS service now validated on NovaSeq6000


RRBS method (Ovation RRBS Methyl-Seq with TrueMethyl oxBS, Tecan) is now tested and validated on NovaSeq6000 for sequencing offering cheaper methylation analysis

Reduced representation bisulfite sequencing (RRBS) is an efficient and high-throughput technique for analysing the genome-wide methylation profiles on a single nucleotide level. GCF has offered an RRBS service using the NextSeq500 instrument. We have now validated this assay using the Illumina NovaSeq6000 platform, which decreases sequencing costs for methylation analysis. The Ovation Methyl-Seq workflow combines stagger to eliminate low sequence diversity and increases base quality and UMI’s to account for non-unique reads from the data set. The required input material is 100 ng genomic DNA, from purified high-quality material to FFPE DNA.

           

 
 
 
 


News

Mar 20, 2024

The Genomics Core Facility has successfully gone through a certification process to become a certified NGS ProLab for TWIST Bioscience technologies. 

Jan 2, 2024

The Genomics Core Facility at Oslo University Hospital and University of Oslo is now a Core Lab for nCounter and GeoMx technologies. 


Contact Information:

Genomics@rr-research.no

Daily Leader Core Facility
Susanne Lorenz, PhD

Susanne.Lorenz@rr-research.no

Head of Core Facility
Leonardo A. Meza-Zepeda, Dr. philos.

L.A.Meza-Zepeda@ous-research.no

Follow us via Twitter

@OSLOmicsCore

Visiting address:

Genomics Core Facility (Room 3-F8-04)
Department of Core facilities
Institute for Cancer Research
New OCCI-building 
 
Norwegian Radium Hospital 
Ullernchaussen 66, Lamell 3, 2B 
NO-0379 Oslo, NORWAY

+47 - 9183 2772 Laboratory
+47 - 9183 3425 Office

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